Pyrimidine nucleosides
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 1MG
2'-Deoxyuridine-1'-13C is a stable isotope-labeled compound with the molecular formula C813CH12N2O5 and a molecular weight of 229.19. It appears as a white to off-white solid with an isotopic enrichment of 99%. This product is intended for research use only and has not been fully validated for medical applications.
- White to off-white solid appearance
- Isotopic enrichment of 99%
- Molecular formula C813CH12N2O5
- Intended for research use only
- Store powder at -20°C for up to 3 years or at 4°C for up to 2 years
- Store in solvent at -80°C for 6 months or at -20°C for 1 month
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 1 G
2'-Deoxyuridine is a brain-penetrant pyrimidine nucleotide associated with nervous system diseases. It can increase chromosome breakage and reduce thymidylate synthetase activity. This compound serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has demonstrated the ability to lessen microglial activation and enhance oxidative stress damage by modulating glycolytic metabolism in brain injury models, indicating its potential for Alzheimer's disease research.
- Brain-penetrant pyrimidine nucleotide.
- Associated with nervous system diseases.
- Can increase chromosome breakage.
- Reduces thymidylate synthetase activity.
- Precursor in synthesis.
- Analogue of other compounds.
- Reduces microglial activation.
- Improves oxidative stress damage.
- Modulates glycolytic metabolism in brain injury.
- Promising for Alzheimer's disease research.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 98.0% | 500 MG
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of bromodeoxyuridine (Brdu).
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Target: endogenous metabolite.
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 5 MG
2'-Deoxyuridine-1'-13C is a carbon-13 labeled version of 2'-Deoxyuridine. This compound induces chromosome breakage, thereby reducing the synthesis activity of thymidylate. Additionally, it serves as a precursor in the synthesis of Edoxudine.
- Carbon-13 labeled version of 2'-Deoxyuridine.
- Induces chromosome breakage.
- Reduces synthesis activity of thymidylate.
- Serves as a precursor in the synthesis of Edoxudine.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | MFCD00006547 | 99.95% | 25 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and is utilized in cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Utilized in cancer research
- Acts as a human endogenous metabolite
- Functions as a microbial metabolite
- Demonstrated to inhibit tumor growth in vivo
Sigma Aldrich Fine Chemicals Biosciences 5-fluoro-2-deoxyuridine 5-5MG
5-fluoro-2-deoxyuridine 5-5MG
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 ML
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Can be used for cancer research
- Intended for research use only
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 50 MG
2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide
- Associated with nervous system diseases
- Increases chromosome breakage
- Decreases thymidylate synthetase activity
- Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
- Promising for Alzheimer's disease (AD) research
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | MFCD00006547 | 99.95% | 50 MG
2'-Deoxycytidine (Standard) is an analytical standard used as a reference for assays. It is commonly employed in various research experiments, including qualitative, quantitative, and methodological studies.
- Serves as a reference standard for assays.
- Utilized in qualitative research experiments.
- Utilized in quantitative research experiments.
- Utilized in methodological research experiments.
- Applicable in HPLC (High-Performance Liquid Chromatography).
- Applicable in GC (Gas Chromatography).
- Applicable in MS (Mass Spectrometry).
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Brdu.
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Inhibits tumor growth in vivo.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | 99.6% | 307.20 | 250 MG
The product, 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid), is an endogenous metabolite and a deoxynucleotide building block of DNA. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: -20°C, protect from light, stored under nitrogen
- In solvent: -80°C for 6 months; -20°C for 1 month (protect from light, stored under nitrogen)
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 5 MG
3'-Deoxycytidine (4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one) is a purine nucleoside analogue. These analogues demonstrate broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analogue
- Broad antitumor activity targeting indolent lymphoid malignancies
- Anticancer mechanisms involve inhibition of DNA synthesis
- Induction of apoptosis